CCL27 Protein (AA 25-112)

Produktnummer ABIN6952170

Produktdetails

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 25-112

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Cell Migration Assay (CMA)

Sequenz: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

Produktmerkmale: Recombinant Human CCL27 (CTACK)

Reinheit: > 97 % by SDS PAGE

Endotoxin-Niveau: <0.01 EU per 1μg of the protein by the LAL method

Biological Activity Comment: EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: 12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution.

Haltbarkeit: 12 months

Antigendetails

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Andere Bezeichnung: CCL27 (CTACK) (CCL27 Produkte)

Hintergrund: Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.

Molekulargewicht: 10.149kDa

UniProt: Q9Y4X3