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CCL3 Protein (AA 24-92) (Biotin)

CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Produktnummer ABIN6952184
  • Target Alle CCL3 Proteine anzeigen
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-92
    Spezies
    • 19
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Human
    Quelle
    • 24
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CCL3 Protein ist gelabelt mit Biotin.
    Applikation
    Cell Migration Assay (CMA)
    Sequenz
    SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
    Produktmerkmale
    Biotininylated Recombinant Human CCL3 (MIP-1alpha)
    Reinheit
    > 97 % by SDS PAGE
    Endotoxin-Niveau
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 1.1-2.6 nM determined by Migration Assay of recombinant CCR5 containing cells
    Top Product
    Discover our top product CCL3 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Haltbarkeit
    12 months
  • Target
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Andere Bezeichnung
    CCL3 (MIP-1alpha) (CCL3 Produkte)
    Synonyme
    MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
    Hintergrund
    Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
    Molekulargewicht
    10.135 kDa
    UniProt
    P10147
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagie
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