CCL3 Protein (AA 24-92)
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- Target Alle CCL3 Proteine anzeigen
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 24-92
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- Cell Migration Assay (CMA)
- Sequenz
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
- Produktmerkmale
- Recombinant Human CCL3 (MIP-1alpha)
- Reinheit
- > 97 % by SDS PAGE
- Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL3 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Haltbarkeit
- 12 months
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- Target
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Andere Bezeichnung
- CCL3 (MIP-1alpha) (CCL3 Produkte)
- Hintergrund
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
- Molekulargewicht
- 7.716 kDa
- UniProt
- P10147
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagie
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