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CCL5 Protein (AA 24-91) (Biotin)

CCL5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Produktnummer ABIN6952202
  • Target Alle CCL5 Proteine anzeigen
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-91
    Spezies
    • 17
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 27
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CCL5 Protein ist gelabelt mit Biotin.
    Applikation
    Cell Migration Assay (CMA)
    Sequenz
    SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
    Produktmerkmale
    Biotininylated Recombinant Human CCL5 (Rantes)
    Reinheit
    > 97 % by SDS PAGE
    Endotoxin-Niveau
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.25-0.50 nM determined by Migration Assay of recombinant CCR5 containing cells
    Top Product
    Discover our top product CCL5 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Haltbarkeit
    12 months
  • Target
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Andere Bezeichnung
    CCL5 (Rantes) (CCL5 Produkte)
    Synonyme
    Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
    Hintergrund
    Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
    Molekulargewicht
    10.270 kDa
    UniProt
    P13501
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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