CCL5 Protein (AA 24-91)
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- Target Alle CCL5 Proteine anzeigen
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 24-91
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- Cell Migration Assay (CMA)
- Sequenz
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
- Produktmerkmale
- Recombinant Human CCL5 (Rantes)
- Reinheit
- > 97 % by SDS PAGE
- Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.13 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL5 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Haltbarkeit
- 12 months
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- Target
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- Andere Bezeichnung
- CCL5 (Rantes) (CCL5 Produkte)
- Hintergrund
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
- Molekulargewicht
- 7.851 kDa
- UniProt
- P13501
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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