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IL-8 Protein (AA 28-99)

IL8 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant CMA Active
Produktnummer ABIN6952234
  • Target Alle IL-8 (IL8) Proteine anzeigen
    IL-8 (IL8) (Interleukin 8 (IL8))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 28-99
    Spezies
    • 27
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 35
    • 13
    • 10
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Cell Migration Assay (CMA)
    Sequenz
    SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
    Produktmerkmale
    Recombinant Human CXCL8 (IL-8)
    Endotoxin-Niveau
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.083 nM determined by Migration Assay in cells expressing recombinant CXCR1
    Top Product
    Discover our top product IL8 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Haltbarkeit
    12 months
  • Target
    IL-8 (IL8) (Interleukin 8 (IL8))
    Andere Bezeichnung
    CXCL8 (IL-8) (IL8 Produkte)
    Synonyme
    CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
    Hintergrund
    Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
    Molekulargewicht
    8.386 kDa
    UniProt
    P10145
    Pathways
    TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
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