IL-8 Protein (AA 28-99)
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- Target Alle IL-8 (IL8) Proteine anzeigen
- IL-8 (IL8) (Interleukin 8 (IL8))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 28-99
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- Cell Migration Assay (CMA)
- Sequenz
- SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
- Produktmerkmale
- Recombinant Human CXCL8 (IL-8)
- Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.083 nM determined by Migration Assay in cells expressing recombinant CXCR1
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Haltbarkeit
- 12 months
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- Target
- IL-8 (IL8) (Interleukin 8 (IL8))
- Andere Bezeichnung
- CXCL8 (IL-8) (IL8 Produkte)
- Hintergrund
- Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
- Molekulargewicht
- 8.386 kDa
- UniProt
- P10145
- Pathways
- TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
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