CD70 Protein (mFc-His Tag)

Produktnummer ABIN6961112

Produktdetails

Target: CD70 (CD70 Molecule (CD70))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD70 Protein ist gelabelt mit mFc-His Tag.

Applikation: ELISA

Verwendungszweck: Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6xHis tag

Spezifität: MFc (Pro99-Lys330) CD70 (Gln39-Pro193) 6xHis

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70 (CD70 Produkte)

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Molekulargewicht: predicted molecular mass of 45.6 kDa after removal of the signal peptide.

Gen-ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints