MST1R Protein (AA 25-957) (Fc Tag)

Produktnummer ABIN6964141

Produktdetails

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-957

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MST1R Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human MST1R Protein with C-terminal Human Fc tag

Spezifität: MST1R (Glu25-Thr957) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Andere Bezeichnung: MST1R (MST1R Produkte)

Synonyme: CD136 Protein, CDw136 Protein, PTK8 Protein, RON Protein, Fv-2 Protein, Fv2 Protein, Ron Protein, STK Protein, Cdw136 Protein, Ptk8 Protein, Stk Protein, macrophage stimulating 1 receptor Protein, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) Protein, MST1R Protein, Mst1r Protein

Hintergrund: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

Molekulargewicht: predicted molecular mass of 125.9 kDa after removal of the signal peptide. The apparent molecular mass of MST1R-hFc is 130-250 kDa due to glycosylation.

UniProt: Q04912

Pathways: RTK Signalweg