PRAME Protein (Fc Tag)
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- Target Alle PRAME Proteine anzeigen
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Protein-Typ
- Recombinant
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PRAME Protein ist gelabelt mit Fc Tag.
- Sequenz
- PRAME (Met1-Asn509)+hFc (Glu99-Ala330)
- Produktmerkmale
- Tagged Protein: C-Human Fc tag
- Aufreinigung
- affinity purification
- Top Product
- Discover our top product PRAME Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Konservierungsmittel
- Without preservative
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Haltbarkeit
- 12 months
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- Target
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Andere Bezeichnung
- PRAME (PRAME Produkte)
- Synonyme
- PRAME Protein, CT130 Protein, MAPE Protein, OIP-4 Protein, OIP4 Protein, 4930534P07Rik Protein, preferentially expressed antigen in melanoma Protein, PRAME Protein, Prame Protein
- Hintergrund
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Synonymes: CT130, MAPE, OIP-4, OIP4
Description: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] - Molekulargewicht
- 81.51 kDa
- UniProt
- P78395
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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