TGFB2 Protein (Fc Tag)
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- Target Alle TGFB2 Proteine anzeigen
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TGFB2 Protein ist gelabelt mit Fc Tag.
- Sequenz
- TGFB2 (Ala303-Ser414)+hFc (Glu99-Ala330)
- Produktmerkmale
- Tagged Protein: C-Human Fc tag
- Aufreinigung
- affinity purification
- Top Product
- Discover our top product TGFB2 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Konservierungsmittel
- Without preservative
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Haltbarkeit
- 12 months
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- Target
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Andere Bezeichnung
- TGFB2 (TGFB2 Produkte)
- Synonyme
- LDS4 Protein, TGF-beta2 Protein, tgf-beta2 Protein, tgfb2-A Protein, BB105277 Protein, Tgf-beta2 Protein, Tgfb-2 Protein, TGF-beta 2 Protein, Tgfbr2T Protein, TGFB2 Protein, TGFbeta2 Protein, MGF Protein, TGF-B2 Protein, transforming growth factor beta 2 Protein, transforming growth factor beta 2 L homeolog Protein, transforming growth factor, beta 2 Protein, transforming growth factor, beta receptor 2 Protein, TGFB2 Protein, tgfb2.L Protein, Tgfb2 Protein, Tgfbr2 Protein, tgfb2 Protein
- Hintergrund
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Synonymes: G-TSF, LDS4, TGF-beta2
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] - Molekulargewicht
- 37.84 kDa
- UniProt
- P61812
- Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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