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Ret Proto-Oncogene Protein (RET) (Fc Tag)

RET Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN6964355
  • Target Alle Ret Proto-Oncogene (RET) Proteine anzeigen
    Ret Proto-Oncogene (RET)
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Ret Proto-Oncogene Protein ist gelabelt mit Fc Tag.
    Sequenz
    RET (Leu29-Arg635)+hFc(GLU99-ALA330)
    Produktmerkmale
    Tagged Protein: C-Human Fc tag
    Aufreinigung
    affinity purification
    Top Product
    Discover our top product RET Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Haltbarkeit
    12 months
  • Target
    Ret Proto-Oncogene (RET)
    Andere Bezeichnung
    RET (RET Produkte)
    Synonyme
    c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein
    Hintergrund
    Synonymes: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
    Description: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017]
    Molekulargewicht
    92.29 kDa
    UniProt
    P07949
    Pathways
    RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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