CD43 Protein (AA 20-253) (Fc Tag)
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- Target Alle CD43 (SPN) Proteine anzeigen
- CD43 (SPN) (Sialophorin (SPN))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-253
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD43 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human CD43 Protein with C-terminal human Fc tag
- Spezifität
- CD43 (Ser20-Arg253) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SPN Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Andere Bezeichnung
- CD43 (SPN Produkte)
- Synonyme
- CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
- Hintergrund
- This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
- Molekulargewicht
- predicted molecular mass of 49.6 kDa after removal of the signal peptide.The apparent molecular mass of CD43-hFc is 55-130 kDa due to glycosylation.
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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