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KREMEN2 Protein (AA 26-364) (His tag)

KREMEN2 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Produktnummer ABIN7013004
  • Target Alle KREMEN2 Proteine anzeigen
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 26-364
    Spezies
    • 4
    • 2
    • 1
    Human
    Quelle
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses KREMEN2 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human Kremen-2 protein, His Tag
    Reinheit
    >95 % as determined by reduced SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product KREMEN2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, 0.2M Arginine, pH 7.4
    Lagerung
    -20 °C
  • Target
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Andere Bezeichnung
    KREMEN2 (KREMEN2 Produkte)
    Synonyme
    krm2 Protein, KREMEN2 Protein, MGC147633 Protein, KRM2 Protein, 2900054E04Rik Protein, Krm2 Protein, kringle containing transmembrane protein 2 S homeolog Protein, kringle containing transmembrane protein 2 Protein, kremen2.S Protein, KREMEN2 Protein, kremen2 Protein, Kremen2 Protein
    Hintergrund
    Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
    Molekulargewicht
    38.0 kDa
    Pathways
    WNT Signalweg
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