PTK7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein
Hintergrund
PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.