SARS-CoV-2 Spike Protein (B.1.617.1 - kappa, RBD) (Fc Tag)
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- Target Alle SARS-CoV-2 Spike Proteine anzeigen
- SARS-CoV-2 Spike
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- B.1.617.1 - kappa, RBD
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Spezies
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SARS-CoV-2 Spike Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- SARS-CoV-2 Spike RBD (L452R, E484Q), Fc Tag (MALS verified)
- Spezifität
- SARS-CoV-2 Spike RBD (L452R, E484Q)
- Produktmerkmale
- SARS-CoV-2 Spike RBD (L452R, E484Q), Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1(L452R, E484Q). The mutations (L452R, E484Q) were identified in the SARS-CoV-2 variants which emerged in India (known as B.1.617).
- Reinheit
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Lagerung
- -20 °C
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- Target
- SARS-CoV-2 Spike
- Abstract
- SARS-CoV-2 Spike Produkte
- Synonyme
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molekulargewicht
- 51.1 kDa
- NCBI Accession
- QHD43416
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