CD8 Protein (CD8) (AA 22-182) (His tag)
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- Target Alle CD8 Proteine anzeigen
- CD8
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-182
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD8 Protein ist gelabelt mit His tag.
- Produktmerkmale
- Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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- Applikationshinweise
- MALS verified
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- CD8
- Andere Bezeichnung
- CD8 alpha & beta (CD8 Produkte)
- Synonyme
- CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, CD8a molecule Protein, CD8A Protein
- Hintergrund
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
- Molekulargewicht
- 19.5 kDa (CD8A) & 22.1 kDa (CD8B)
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