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IL-8 Protein (AA 28-99) (Fc Tag)
IL8
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
Produktnummer ABIN7013452
Produktdetails
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Target
Alle IL-8 (IL8) Proteine anzeigen
IL-8 (IL8)
(Interleukin 8 (IL8))
Protein-Typ
Recombinant
Biologische Aktivität
Active
Proteineigenschaft
AA 28-99
Spezies
Alle Spezies für IL-8 Proteine
Human
Quelle
Alle Expressionssysteme für IL-8 Proteine
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses IL-8 Protein ist gelabelt mit Fc Tag.
Produktmerkmale
Human IL-8 / CXCL8 Protein, Fc Tag
Reinheit
>95 % as determined by SDS-PAGE.
Endotoxin-Niveau
Less than 1.0 EU per μg by the LAL method.
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Discover our top product IL8 Protein
Alternativen
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Lyophilized
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
Lagerung
-20 °C
Antigendetails
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Target
IL-8 (IL8)
(Interleukin 8 (IL8))
Andere Bezeichnung
IL-8 (IL8 Produkte )
Synonyme
CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
Hintergrund
Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Molekulargewicht
34.8 kDa
NCBI Accession
NP_000575
Pathways
TLR Signalweg , Cellular Response to Molecule of Bacterial Origin , Regulation of G-Protein Coupled Receptor Protein Signaling , ER-Nucleus Signaling , Hepatitis C , Autophagie
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