Factor VII Protein (AA 61-466) (His tag)

Produktnummer ABIN7013840

Produktdetails

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 61-466

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Factor VII Protein ist gelabelt mit His tag.

Verwendungszweck: Human Coagulation factor VII / F7 Protein, His Tag (active enzyme, MALS verified)

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris,150 mM NaCl, pH 7.5

Lagerung: -20 °C

Antigendetails

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: Coagulation factor VII (F7 Produkte)

Synonyme: F7 Protein, wu:fb59f04 Protein, zgc:109870 Protein, SPCA Protein, AI114908 Protein, ATIII Protein, At-3 Protein, At3 Protein, LOC100223776 Protein, AI132620 Protein, Cf7 Protein, FVII Protein, mfVII Protein, f7 Protein, coagulation factor VII Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog Protein, F7 Protein, f7 Protein, Serpinc1 Protein, CpipJ_CPIJ009142 Protein, CpipJ_CPIJ010295 Protein, CpipJ_CPIJ020127 Protein, fa7 Protein, f7.S Protein

Hintergrund: Coagulation factor VII is also known as F7, SPCA and Proconvertin. Heterodimer of a light chain and a heavy chain linked by a disulfide bond. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

Molekulargewicht: 47.1 kDa

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling