SARS-CoV-2 Spike Protein (BA.2 - Omicron) (His tag)
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- Target Alle SARS-CoV-2 Spike Proteine anzeigen
- SARS-CoV-2 Spike
- Protein-Typ
- Recombinant
- Proteineigenschaft
- BA.2 - Omicron
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Spezies
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SARS-CoV-2 Spike Protein ist gelabelt mit His tag.
- Applikation
- ELISA, SDS-PAGE (SDS)
- Verwendungszweck
- SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) (MALS verified)
- Produktmerkmale
- SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L). This protein carries a polyhistidine tag at the C-terminus.
- Reinheit
- > 95% as determined by SDS-PAGE. > 90% as determined by SEC-MALS.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike Protein
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- Kommentare
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The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C/-80 °C
- Informationen zur Lagerung
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For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 months under sterile conditions after reconstitution. - Haltbarkeit
- 12 monts
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- Target
- SARS-CoV-2 Spike
- Abstract
- SARS-CoV-2 Spike Produkte
- Synonyme
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molekulargewicht
- 26.7 kDa
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