CD36 Protein (CD36) (AA 30-439) (Fc Tag)

Produktnummer ABIN7092680

Produktdetails

Target: CD36

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-439

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD36 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human CD36 Protein with C-terminal human Fc tag

Spezifität: CD36 (Gly30-Asn439) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CD36

Andere Bezeichnung: CD36 (CD36 Produkte)

Synonyme: BDPLT10 Protein, CHDS7 Protein, FAT Protein, GP3B Protein, GP4 Protein, GPIV Protein, PASIV Protein, SCARB3 Protein, Fat Protein, Scarb3 Protein, GPIIIB Protein, PAS-4 Protein, zgc:92513 Protein, CD36 molecule Protein, CD36 molecule (thrombospondin receptor) Protein, CD36 Protein, Cd36 Protein, cd36 Protein

Hintergrund: The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: predicted molecular mass of 72.8 kDa after removal of the signal peptide.The apparent molecular mass of CD36-hFc is 100-130 kDa due to glycosylation.

UniProt: P16671

Pathways: TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteine