F11R Protein (AA 28-238) (Fc Tag)
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- Target Alle F11R Proteine anzeigen
- F11R (F11 Receptor (F11R))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 28-238
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses F11R Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human JAM-A Protein with C-terminal human Fc tag
- Spezifität
- JAM-A (Ser28-Val238) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product F11R Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- F11R (F11 Receptor (F11R))
- Andere Bezeichnung
- JAM-A (F11R Produkte)
- Synonyme
- CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
- Hintergrund
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
- Molekulargewicht
- predicted molecular mass of 49.1 kDa after removal of the signal peptide.The apparent molecular mass of JAM-A-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q9Y624
- Pathways
- Cell-Cell Junction Organization
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