BCL2L1 Protein (AA 1-212) (Fc Tag)
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- Target Alle BCL2L1 Proteine anzeigen
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-212
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses BCL2L1 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant human BCL2L1 protein with C-terminal human Fc tag
- Spezifität
- BCL2L1 (Met1-Arg212) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product BCL2L1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Andere Bezeichnung
- BCL2L1 (BCL2L1 Produkte)
- Synonyme
- BCL-XL/S Protein, BCL2L Protein, BCLX Protein, BCLXL Protein, BCLXS Protein, Bcl-X Protein, PPP1R52 Protein, bcl-xL Protein, bcl-xS Protein, Bcl(X)L Protein, Bcl-XL Protein, Bcl-Xs Protein, Bcl2l Protein, BclX Protein, bcl-x Protein, Bcl-xl Protein, Bclx Protein, bcl-X Protein, Bcl-xL Protein, BCL-XL Protein, BCL2L1 Protein, bcl-XL Protein, bcl-x(l) Protein, bcl-xl/s Protein, bcl-xs Protein, bcl2l Protein, bclx Protein, bclxl Protein, xR11 Protein, bcl-xl Protein, blp1 Protein, cb1021 Protein, zfBLP1 Protein, BCL2 like 1 Protein, BCL2-like 1 Protein, Bcl2-like 1 Protein, BCL2-like 1 L homeolog Protein, bcl2-like 1 Protein, BCL2L1 Protein, Bcl2l1 Protein, bcl2l1 Protein, bcl2l1.L Protein
- Hintergrund
- The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
- Molekulargewicht
- predicted molecular mass of 49.9 kDa after removal of the signal peptide.The apparent molecular mass of BCL2L1-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q07817
- Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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