NEFL Protein (AA 9-88) (Fc Tag)
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- Target Alle NEFL Proteine anzeigen
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 9-88
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses NEFL Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human NEFL(9-88) with C-terminal human Fc tag
- Spezifität
- NEFL (Thr9-Thr88) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- Andere Bezeichnung
- NEFL (NEFL Produkte)
- Synonyme
- NEFL Protein, nefl Protein, zgc:136626 Protein, AI847934 Protein, CMT2E Protein, NF-L Protein, NF68 Protein, Nfl Protein, CMT1F Protein, NFL Protein, XNF-L Protein, neurofilament light Protein, neurofilament, light polypeptide Protein, neurofilament, light polypeptide b Protein, neurofilament, light L homeolog Protein, NEFL Protein, neflb Protein, Nefl Protein, nefl.L Protein
- Hintergrund
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Molekulargewicht
- predicted molecular mass of 34.9 kDa after removal of the signal peptide. The apparent molecular mass of NEFL(9-88)-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P07196
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