PADI2
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 78.3 kDa. The protein migrates as 66-70 kDa under reducing (R) condition due to glycosylation.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 1 mM EDTA, 0.5 mM TCEP, pH 7.4
Lagerung
-80 °C
Informationen zur Lagerung
-70°C
Target
PADI2
(Peptidyl Arginine Deiminase, Type II (PADI2))
PADI2 Protein, PAD-H19 Protein, PAD2 Protein, PDI2 Protein, Pdi Protein, Pdi2 Protein, mKIAA0994 Protein, peptidyl arginine deiminase 2 Protein, peptidyl arginine deiminase, type II Protein, protein-arginine deiminase type-2 Protein, peptidyl arginine deiminase, type II S homeolog Protein, PADI2 Protein, padi2 Protein, LOC100357368 Protein, padi2.S Protein, Padi2 Protein
Hintergrund
Synonyms: PADI2,PAD-H19,KIAA0994,PAD2,PDI2, Description: Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.