Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Applikationshinweise
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 57-66 kDa under reducing (R) condition due to glycosylation.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
PBS, pH 7.4
Lagerung
-20 °C
Informationen zur Lagerung
-20°C
Target
IFN-alpha/beta R1
Andere Bezeichnung
IFN-alpha / beta R1
Hintergrund
Synonyms: IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1, Description: Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.