KIR3DL3
Spezies: Human
Wirt: Mammalian Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Crystallography grade
KIR3DL3
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
Crystallography grade
KIR3DL3
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
KIR3DL3
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
90 %
Applikationshinweise
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition due to glycosylation.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
Lagerung
-20 °C
Informationen zur Lagerung
-20°C
Target
KIR3DL3
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
CD158Z Protein, KIR3DL7 Protein, KIR44 Protein, KIRC1 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 Protein, KIR3DL3 Protein
Hintergrund
Synonyms: Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1, Description: the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [