MPXV E8L protein (His tag)

Produktnummer ABIN7126002

Produktdetails

Target: MPXV E8L

Protein-Typ: Recombinant

Spezies: Monkeypox Virus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Monkeypox virus (strain Zaire-96-I-16) E8L Protein, His Tag

Sequenz: Met 1 - Thr 275

Produktmerkmale: Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Thr 275 (Accession # Q8V4Y0-1).

Reinheit: >90% as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 0.01 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.7 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Lagerung: -20 °C

Antigendetails

Target: MPXV E8L

Hintergrund: Synonyms: E8L,
Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa , multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. E8L can Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell.

Molekulargewicht: 33.7 kDa