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IL17C Protein (His tag)

IL17C Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN7194048
  • Target Alle IL17C Proteine anzeigen
    IL17C (Interleukin 17C (IL17C))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 3
    • 2
    • 1
    Maus
    Quelle
    • 7
    • 6
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL17C Protein ist gelabelt mit His tag.
    Verwendungszweck
    Mouse IL-17C Protein, His Tag
    Sequenz
    Asp 17 - Gln 194
    Produktmerkmale
    Mouse IL-17C, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Gln 194 (Accession # Q8K4C5-1).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL17C Protein
  • Applikationshinweise
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 25-27 kDa under reducing (R) condition due to glycosylation.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, 0.5 M Arginine, pH 7.4
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Target
    IL17C (Interleukin 17C (IL17C))
    Andere Bezeichnung
    IL-17C (IL17C Produkte)
    Synonyme
    IL17C Protein, il17-3 Protein, CX2 Protein, IL-17C Protein, IL-21 Protein, interleukin 17C Protein, interleukin 17c Protein, IL17C Protein, il17c Protein, Il17c Protein
    Hintergrund
    Synonyms: IL-17C,Cytokine CX2,IL17C,
    Description: Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
    Molekulargewicht
    21.7 kDa
    NCBI Accession
    NP_665833
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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