Afamin Protein (AFM) (His tag)

Produktnummer ABIN7319846

Produktdetails

Target: Afamin (AFM)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Afamin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Afamin/AFM (C-6His)

Sequenz: Leu22-Asn599

Produktmerkmale: Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Afamin (AFM)

Andere Bezeichnung: Afamin/AFM (AFM Produkte)

Synonyme: AFM Protein, ALB2 Protein, ALBA Protein, ALF Protein, Alf Protein, alpha-Alb Protein, afamin Protein, AFM Protein, Afm Protein

Hintergrund:

Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.

Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin

Molekulargewicht: 67.6 kDa

UniProt: P43652