AGRP Protein (His tag)
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- Target Alle AGRP Proteine anzeigen
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses AGRP Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human AgRP/AGRP Protein (His Tag)
- Sequenz
- Met 1-Thr 132
- Produktmerkmale
- A DNA sequence encoding the human AgRP (NP_001129.1) (Met 1-Thr 132) was expressed,with a polyhistidine tag at the C-terminus.
- Reinheit
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AGRP Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.2
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Andere Bezeichnung
- AgRP/AGRP (AGRP Produkte)
- Synonyme
- AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
- Hintergrund
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Background: Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
Synonym: AGRT,ART,ASIP2
- Molekulargewicht
- 14 kDa
- NCBI Accession
- NP_001129
- Pathways
- Feeding Behaviour, Photoperiodism
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