Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ALDH4A1 Protein

ALDH4A1 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7194202
  • Target Alle ALDH4A1 Proteine anzeigen
    ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
    Protein-Typ
    Recombinant
    Spezies
    • 2
    • 1
    Human
    Quelle
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Verwendungszweck
    Recombinant Human ALDH4A1 Protein
    Sequenz
    Lys 25-Gln 563
    Produktmerkmale
    A DNA sequence encoding the human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ALDH4A1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.5
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
    Andere Bezeichnung
    ALDH4A1 (ALDH4A1 Produkte)
    Synonyme
    aldh4 Protein, p5cd Protein, p5cdh Protein, ALDH4 Protein, P5CD Protein, P5CDh Protein, A930035F14Rik Protein, Ahd-1 Protein, Ahd1 Protein, Aldh4 Protein, Aldh5a1 Protein, E330022C09 Protein, P5cd Protein, P5cdh Protein, P5cdhl Protein, P5cdhs Protein, Ssdh1 Protein, zgc:63592 Protein, aldehyde dehydrogenase 4 family member A1 Protein, aldehyde dehydrogenase 4 family, member A1 Protein, aldehyde dehydrogenase 4 family member A1 L homeolog Protein, aldh4a1 Protein, ALDH4A1 Protein, Aldh4a1 Protein, aldh4a1.L Protein
    Hintergrund

    Background: ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.

    Synonym: ALDH4,P5CD,P5CDh

    Molekulargewicht
    59.2 kDa
    Pathways
    Monocarboxylic Acid Catabolic Process
Sie sind hier:
Kundenservice