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Amphiregulin Protein (AREG)

AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318151
  • Target Alle Amphiregulin (AREG) Proteine anzeigen
    Amphiregulin (AREG)
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 17
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Verwendungszweck
    Recombinant Human Amphiregulin/AREG Protein
    Sequenz
    Ser101-Lys198
    Produktmerkmale
    Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product AREG Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Amphiregulin (AREG)
    Andere Bezeichnung
    Amphiregulin/AREG (AREG Produkte)
    Synonyme
    AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
    Hintergrund

    Background: Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.

    Synonym: Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB

    Molekulargewicht
    11.4 kDa
    UniProt
    P15514
    Pathways
    RTK Signalweg, EGFR Signaling Pathway
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