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BCL2L2 Protein (His tag)

BCL2L2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318198
  • Target Alle BCL2L2 Proteine anzeigen
    BCL2L2 (BCL2-Like 2 (BCL2L2))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 2
    • 2
    • 1
    Human
    Quelle
    • 11
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BCL2L2 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human BCL-W/BCL2L2 Protein (His Tag)
    Sequenz
    Ala2-Thr172
    Produktmerkmale
    Recombinant Human B Cell Lymphoma/Leukemia w is produced by our E.coli expression system and the target gene encoding Ala2-Thr172 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BCL2L2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 25 mM HEPES, 100 mM KCl, 20 % Glycerol, pH 7.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    BCL2L2 (BCL2-Like 2 (BCL2L2))
    Andere Bezeichnung
    BCL-W/BCL2L2 (BCL2L2 Produkte)
    Synonyme
    bcl2l2 Protein, BCL2L2 Protein, BCL-W Protein, BCL2-L-2 Protein, BCLW Protein, PPP1R51 Protein, AW048834 Protein, Bcl-w Protein, Gtrgal2 Protein, Gtrosa41 Protein, bclw Protein, c98 Protein, BCL-WEL Protein, BCL-WS Protein, Bclw Protein, bcl-w Protein, bcl2l2-a Protein, bcl2l2-b Protein, xr1 Protein, BCL2 like 2 Protein, BCL2-like 2 Protein, BCL2 like 12 Protein, Bcl2-like 2 Protein, bcl-2-like protein 2 Protein, BCL2-like 2 L homeolog Protein, BCL2L2 Protein, bcl2l2 Protein, BCL2L12 Protein, Bcl2l2 Protein, LOC100154044 Protein, LOC100345100 Protein, bcl2l2.L Protein
    Hintergrund

    Background: Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.

    Synonym: Bcl-2-Like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCL2L2, BCLW, KIAA0271

    Molekulargewicht
    19.9 kDa
    UniProt
    Q92843
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