CREB3L1 Protein (AA 396-519) (His tag)
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- Target Alle CREB3L1 Proteine anzeigen
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 396-519
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CREB3L1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human CREB3L1/OASIS Protein (aa 396-519, His Tag)
- Sequenz
- Glu396-Ser519
- Produktmerkmale
- A DNA sequence encoding the human CREB3L1 (Q96BA8-1) (Glu396-Ser519) was expressed with a polyhistidine tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CREB3L1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, PH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- Andere Bezeichnung
- CREB3L1/OASIS (CREB3L1 Produkte)
- Synonyme
- CREB3L1 Protein, OASIS Protein, Oasis Protein, diacylglycerol kinase-like Protein, cAMP responsive element binding protein 3 like 1 Protein, cAMP responsive element binding protein 3-like 1 Protein, LOC423198 Protein, CREB3L1 Protein, Creb3l1 Protein
- Hintergrund
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Background: CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.
Synonym: OASIS,PSEC0238
- Molekulargewicht
- 15.2 kDa
- Pathways
- Thyroid Hormone Synthesis, Chromatin Binding
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