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CPE Protein (His tag)

CPE Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318246
  • Target Alle CPE Proteine anzeigen
    CPE (Carboxypeptidase E (CPE))
    Protein-Typ
    Recombinant
    Spezies
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 4
    • 4
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CPE Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Carboxypeptidase E/CPE Protein (His Tag)
    Sequenz
    Arg42-Ser453
    Produktmerkmale
    Recombinant Human Carboxypeptidase E is produced by our Mammalian expression system and the target gene encoding Arg42-Ser453 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CPE Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM ZnCl2,10 % Glycerol, pH 7.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    CPE (Carboxypeptidase E (CPE))
    Andere Bezeichnung
    Carboxypeptidase E/CPE (CPE Produkte)
    Synonyme
    CPE Protein, CPH Protein, Cph-1 Protein, Cph1 Protein, R74677 Protein, fat Protein, CARBE Protein, Cph Protein, si:ch211-198g9.2 Protein, zgc:85981 Protein, carboxypeptidase E Protein, carboxypeptidase E L homeolog Protein, CPE Protein, cpe Protein, Cpe Protein, cpe.L Protein
    Hintergrund

    Background: The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.

    Synonym: Carboxypeptidase E(CPE for short), Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase

    Molekulargewicht
    47.1 kDa
    UniProt
    P16870
    Pathways
    Peptide Hormone Metabolism, Synaptic Membrane
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