Cathepsin B Protein (CTSB) (AA 18-339) (His tag)
Kurzübersicht für Cathepsin B Protein (CTSB) (AA 18-339) (His tag) (ABIN7318252)
Target
Alle Cathepsin B (CTSB) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 18-339
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Aufreinigungstag / Konjugat
- Dieses Cathepsin B Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Cathepsin B/CTSB Protein (His Tag)
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Sequenz
- Arg18-Ile339
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Produktmerkmale
- Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Cathepsin B (CTSB) (AA 18-339) (Active) protein (His tag)
CTSB Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 90 % SDS, EAA Active
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Cathepsin B (CTSB) (AA 1-339) protein (His tag)CTSB Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Cathepsin B (CTSB) (Active) protein (His tag)CTSB Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Cathepsin B (CTSB) (AA 1-339) protein (GST tag)CTSB Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Cathepsin B (CTSB) (AA 21-339) protein (GST tag)CTSB Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Cathepsin B (CTSB) (AA 82-333), (partial) protein (GST tag)CTSB Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 8 % Sucrose, 0.05 % Tween 80, pH 7.4.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- Cathepsin B (CTSB)
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Andere Bezeichnung
- Cathepsin B/CTSB
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Hintergrund
- APP Secretase,APPS,CPSB,CTSB,Cathepsin B,Cathepsin B1,Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
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Molekulargewicht
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Calculated MW: 36.9 kDa
Observed MW: 34&38-50 kDa
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Gen-ID
- 1508
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UniProt
- P07858
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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