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Cathepsin D Protein (CTSD) (His tag)

CTSD Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Produktnummer ABIN7320739
  • Target Alle Cathepsin D (CTSD) Proteine anzeigen
    Cathepsin D (CTSD)
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Cathepsin D Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
    Sequenz
    Ile21-Leu410
    Produktmerkmale
    Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by SDS-PAGE
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSD Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Cathepsin D (CTSD)
    Andere Bezeichnung
    Cathepsin D/CTSD (CTSD Produkte)
    Synonyme
    catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
    Hintergrund

    Background: CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.

    Synonym: Cathepsin D, CTSD,CPSD

    Molekulargewicht
    43.9 kDa
    NCBI Accession
    NP_034113
    Pathways
    Peptide Hormone Metabolism
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