Cathepsin L Protein (His tag)

Produktnummer ABIN7318255

Produktdetails

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Cathepsin L Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cathepsin L/CTSL Protein (His Tag)

Sequenz: Thr18-Val333

Produktmerkmale: Recombinant Human Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Val333 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L/CTSL (CTSL1 Produkte)

Hintergrund:

Background: Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.

Synonym: Cathepsin L1, Major Excreted Protein, MEP, CTSL1, CTSL

Molekulargewicht: 36.9 kDa

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades