CD59a Protein (CD59A) (His tag)
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- Target Alle CD59a (CD59A) Proteine anzeigen
- CD59a (CD59A)
- Protein-Typ
- Recombinant
- Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD59a Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse CD59a/MAC-IP Protein (His Tag)
- Sequenz
- Met 1-Lys 95
- Produktmerkmale
- A DNA sequence encoding the mouse CD59a (O55186) (Met 1-Lys 95), without the pro peptide, was fused with a C-terminal polyhistidine tag.
- Reinheit
- > 92 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CD59A Protein
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CD59a (CD59A) (AA 24-96) protein (Fc Tag)
CD59A Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD59a (CD59A)
- Andere Bezeichnung
- CD59a/MAC-IP (CD59A Produkte)
- Synonyme
- AA987121 Protein, Cd59 Protein, protectin Protein, CD59a antigen Protein, Cd59a Protein
- Hintergrund
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Background: Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins.It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor, it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.
Synonym: AA987121,Cd59,protectin,RP24-297H17.1
- Molekulargewicht
- 9.7 kDa
- UniProt
- O55186
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