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CD6 Protein (CD6) (His tag)

CD6 Spezies: Maus Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7320847
  • Target Alle CD6 Proteine anzeigen
    CD6
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 2
    • 1
    Maus
    Quelle
    • 8
    • 3
    • 2
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD6 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Mouse CD6/TP120 Protein (His Tag)
    Sequenz
    Leu18-Gly396
    Produktmerkmale
    Recombinant Mouse CD6 antigen is produced by our Mammalian expression system and the target gene encoding Leu18-Gly396 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD6 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD6
    Andere Bezeichnung
    CD6/TP120 (CD6 Produkte)
    Synonyme
    TP120 Protein, OX52 Protein, CD6 antigen Protein, CD6 molecule Protein, Cd6 molecule Protein, Cd6 Protein, CD6 Protein
    Hintergrund

    Background: CD6 is a member of the group B scavenger receptor cysteinerich(SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellularSRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subsetof B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatorymolecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However,the signaling pathways have not been elucidated.

    Synonym: CD6 antigen, Cd6

    Molekulargewicht
    41.9 kDa
    UniProt
    Q91WN5
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