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CD82 Protein (CD82) (Fc Tag)

CD82 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319825
  • Target Alle CD82 Proteine anzeigen
    CD82
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 2
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD82 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human CD82 (N-Fc)
    Sequenz
    Gly103-Gln225
    Produktmerkmale
    Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD82 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD82
    Andere Bezeichnung
    CD82 (CD82 Produkte)
    Synonyme
    AA682076 Protein, AL023070 Protein, C33 Protein, IA4 Protein, Kai1 Protein, Tspan27 Protein, 4F9 Protein, GR15 Protein, KAI1 Protein, R2 Protein, SAR2 Protein, ST6 Protein, TSPAN27 Protein, CD82 antigen Protein, CD82 molecule Protein, Cd82 molecule Protein, Cd82 Protein, CD82 Protein
    Hintergrund

    Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

    Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9

    Molekulargewicht
    40.3 kDa
    UniProt
    P27701
    Pathways
    p53 Signalweg
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