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CD8B Protein (Fc Tag)

CD8B Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319847
  • Target Alle CD8B Proteine anzeigen
    CD8B (CD8b Molecule (CD8B))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD8B Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human CD8 Beta Chain/CD8B (C-Fc)
    Sequenz
    Leu22-Pro170
    Produktmerkmale
    Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD8B Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD8B (CD8b Molecule (CD8B))
    Andere Bezeichnung
    CD8 Beta Chain/CD8B (CD8B Produkte)
    Synonyme
    Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
    Hintergrund

    Background: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

    Synonym: T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b, CD8B, CD8B1

    Molekulargewicht
    43.7 kDa
    UniProt
    P10966
    Pathways
    T-Zell Rezeptor Signalweg
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