CCL22 Protein (His tag)
-
- Target Alle CCL22 Proteine anzeigen
- CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses CCL22 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human CCL22/MDC Protein (His Tag)
- Sequenz
- Gly 25-Gln 93
- Produktmerkmale
- A DNA sequence encoding the secreeted form of human CCL22 (O00626) (Gly 25-Gln 93) was expressed, with a polyhistidine tag at the N-terminus.
- Reinheit
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CCL22 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 30 % Acetonitrile, 0.1 % TFA
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
- Andere Bezeichnung
- CCL22/MDC (CCL22 Produkte)
- Synonyme
- ABCD-1 Protein, DC/B-CK Protein, MDC Protein, SCYA22 Protein, STCP-1 Protein, DCBCK Protein, Scya22 Protein, Mdc Protein, CCL22 Protein, C-C motif chemokine ligand 22 Protein, chemokine (C-C motif) ligand 22 Protein, CCL22 Protein, Ccl22 Protein
- Hintergrund
-
Background: Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated / effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1 / CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine.
Synonym: A-152E5.1,ABCD-1,DC/B-CK,MDC,SCYA22,STCP-1
- Molekulargewicht
- 9.7 kDa
- UniProt
- O00626
-