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Elastase 4 Protein (His tag)

CTRC Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319317
  • Target Alle Elastase 4 (CTRC) Produkte
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 3
    • 1
    Human
    Quelle
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Elastase 4 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Chymotrypsin C Protein (His Tag)
    Sequenz
    Cys17-Leu268
    Produktmerkmale
    Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    Andere Bezeichnung
    Chymotrypsin C (CTRC Produkte)
    Synonyme
    CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
    Hintergrund

    Background: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.

    Synonym: Chymotrypsin-C, Caldecrin, CTRC, CLCR

    Molekulargewicht
    29.0 kDa
    UniProt
    Q99895
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