COL6a3 Protein (His tag)
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- Target Alle COL6a3 Proteine anzeigen
- COL6a3 (Collagen, Type VI, alpha 3 (COL6a3))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses COL6a3 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human COL6A3/Collagen-VI Protein (His Tag)
- Sequenz
- 3101T-3177T
- Produktmerkmale
- A DNA sequence encoding the BPTI/Kunitz inhibitor domain of human COL6A3 (P12111-1) (3101T-3177T) was expressed with an N-terminal polyhistidine tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product COL6a3 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- COL6a3 (Collagen, Type VI, alpha 3 (COL6a3))
- Andere Bezeichnung
- COL6A3/Collagen-VI (COL6a3 Produkte)
- Synonyme
- wu:fb06e12 Protein, wu:fs74g09 Protein, COL6A3 Protein, AI507288 Protein, Col6a-3 Protein, collagen type VI alpha 3 chain Protein, collagen, type VI, alpha 3 Protein, COL6A3 Protein, col6a3 Protein, Col6a3 Protein
- Hintergrund
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Background: This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described.
Synonym: COL6A3,Collagen-VI
- Molekulargewicht
- 11.4 kDa
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