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Contactin 4 Protein (CNTN4) (His tag)

CNTN4 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317984
  • Target Alle Contactin 4 (CNTN4) Proteine anzeigen
    Contactin 4 (CNTN4)
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 2
    • 1
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    Dieses Contactin 4 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Contactin 4/CNTN4 Protein (His Tag)
    Sequenz
    Met 1-Ser 1000
    Produktmerkmale
    A DNA sequence encoding the mature form of human CNTN4 isoform 1 (Q8IWV2-1) (Met 1-Ser 1000) was fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CNTN4 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % gly
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Contactin 4 (CNTN4)
    Andere Bezeichnung
    Contactin 4/CNTN4 (CNTN4 Produkte)
    Synonyme
    Axcam Protein, Big-2 Protein, AXCAM Protein, BIG-2 Protein, 9630050B05 Protein, FAR-1 Protein, MGC84491 Protein, zgc:153573 Protein, axcam Protein, big-2 Protein, cntn4a Protein, contactin 4 Protein, contactin 4 S homeolog Protein, Cntn4 Protein, CNTN4 Protein, cntn4.S Protein, cntn4 Protein
    Hintergrund

    Background: Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences. 

    Synonym: AXCAM;BIG-2

    Molekulargewicht
    110 kDa
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