ENPP2 Protein (AA 36-863) (His tag)
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- Target Alle ENPP2 Proteine anzeigen
- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 36-863
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses ENPP2 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Autotaxin/ENPP2 Protein (aa 36-863, His Tag)
- Sequenz
- Ala36-Ile863
- Produktmerkmale
- Recombinant Human ENPP2 is produced by our Mammalian expression system and the target gene encoding Ala36-Ile863 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ENPP2 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mMPB,150 mMNaCl, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
- Andere Bezeichnung
- Autotaxin/ENPP2 (ENPP2 Produkte)
- Synonyme
- ATX Protein, ATX-X Protein, AUTOTAXIN Protein, LysoPLD Protein, NPP2 Protein, PD-IALPHA Protein, PDNP2 Protein, Npps2 Protein, PD-Ialpha Protein, Pdnp2 Protein, MGC132047 Protein, atx Protein, zgc:63550 Protein, autotaxin Protein, enpp2 Protein, enpp2a Protein, enpp2b Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog Protein, ENPP2 Protein, Enpp2 Protein, enpp2 Protein, enpp2.L Protein, enpp2.S Protein
- Hintergrund
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Background: ENPP-2, also known as Autotaxin, belongs to the ectonucleotide pyrophosphatase/phosphodiesterase (NPP) family. Some NPPs hydrolyze phosphates from nucleotides and their derivatives. ENPP-2 shares 40 - 50 % identity to ENPP1 & 3, all of which contain a N-terminal intracellular domain, a single transmembrane domain and a large extracellular domain that includes a catalytic domain, two somatomedin-B-like domains, and a C-terminal nuclease-like domain.Evidence shows LPA and sphingosine 1-phosphate to be specific inhibitors of ENPP-2. ENPP-2 was originally found to stimulate tumor cell motility and has since been found to enhance tumor invasion and metastasis and to be up-regulated in several types of carcinomas including breast and lung.
Synonym: ATX, ATXFLJ26803, ATX-X, Autotaxin, autotaxin-t, EC 3.1.4.39, ectonucleotide pyrophosphatase/phosphodiesterase 2,E-NPP 2, ENPP2, LysoPLD, NPP2, PD-IALPHA, PDNP2, PDNP2NPP2
- Molekulargewicht
- 90 kDa
- UniProt
- Q13822
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