EPH Receptor A6 Protein (Epha6) (His tag)
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- Target Alle EPH Receptor A6 (Epha6) Proteine anzeigen
- EPH Receptor A6 (Epha6)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses EPH Receptor A6 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse EphA6/EHK-2 Protein (His Tag)(Active)
- Sequenz
- Met 1-Gln 546
- Produktmerkmale
- A DNA sequence encoding the extracellular domain of mouse EphA6 (NP_031964.2) (Met 1-Gln 546) was expressed, with a C-terminal polyhistidine tag.
- Reinheit
- > 97 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse EphA6 at 2 μg/ml (100 μl/well) can bind recombinant human EphrinA3 at a linear range of 0.31-10 ng/ml.
- Top Product
- Discover our top product Epha6 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- EPH Receptor A6 (Epha6)
- Andere Bezeichnung
- EphA6/EHK-2 (Epha6 Produkte)
- Synonyme
- EPHA6 Protein, Ehk2 Protein, Hek12 Protein, m-ehk2 Protein, EHK-2 Protein, EHK2 Protein, EK12 Protein, EPA6 Protein, HEK12 Protein, PRO57066 Protein, EPH receptor A6 Protein, Eph receptor A6 Protein, EPHA6 Protein, epha6 Protein, Epha6 Protein
- Hintergrund
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Background: Ephrin type-A receptor 6, also known as EphA6 or EHK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph receptor−mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. In the vomeronasal system, Ephrin-A5/EphA6 interactions mediate attraction or adhesion rather than repulsion.
Synonym: Ehk2;Hek12;m-ehk2
- Molekulargewicht
- 59.5 kDa
- NCBI Accession
- NP_031964
- Pathways
- RTK Signalweg
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