F11R Protein (His tag)
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- Target Alle F11R Proteine anzeigen
- F11R (F11 Receptor (F11R))
- Protein-Typ
- Recombinant
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Spezies
- Ratte
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses F11R Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Rat JAM-A/F11R Protein (His Tag)
- Sequenz
- Met1-Gly238
- Produktmerkmale
- A DNA sequence encoding the rat F11R (Q9JHY1) (Met1-Gly238) was expressed with a polyhistidine tag at the C-terminus.
- Reinheit
- > (23.7+75.2) % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product F11R Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- F11R (F11 Receptor (F11R))
- Andere Bezeichnung
- JAM-A/F11R (F11R Produkte)
- Synonyme
- CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
- Hintergrund
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Background: Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
Synonym: F11R,Jam1
- Molekulargewicht
- 24.3 kDa
- UniProt
- Q9JHY1
- Pathways
- Cell-Cell Junction Organization
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