FABP4 Protein (His tag)
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- Target Alle FABP4 Proteine anzeigen
- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses FABP4 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse FABP4/A-FABP Protein (HEK293, His Tag)
- Sequenz
- Met 1-Ala 132
- Produktmerkmale
- A DNA sequence encoding the mouse FABP4 (NP_077717.1) (Met 1-Ala 132) was expressed, with a C-terminal polyhistidine tag.
- Reinheit
- > 85 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product FABP4 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
- Andere Bezeichnung
- FABP4/A-FABP (FABP4 Produkte)
- Synonyme
- A-FABP Protein, AFABP Protein, ALBP Protein, aP2 Protein, LOC100223994 Protein, FABP Protein, AP2 Protein, FABP3 Protein, FABP4 Protein, MGC84940 Protein, fabp4 Protein, 422/aP2 Protein, ALBP/Ap2 Protein, Ap2 Protein, Lbpl Protein, Albp Protein, fatty acid binding protein 4 Protein, fatty acid-binding protein, adipocyte Protein, fatty acid binding protein 4, adipocyte Protein, fatty acid binding protein 4, adipocyte L homeolog Protein, Fatty acid-binding protein, adipocyte Protein, adipocyte fatty acid-binding protein Protein, adipocyte fatty acid binding protein Protein, FABP4 Protein, LOC100223994 Protein, fabp4.L Protein, fabp4 Protein, Fabp4 Protein, LOC100732353 Protein, LOC100861279 Protein, LOC100057425 Protein, LOC395224 Protein
- Hintergrund
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Background: Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.
Synonym: 422/aP2;ALBP/Ap2;Ap2;Lbpl
- Molekulargewicht
- 16 kDa
- NCBI Accession
- NP_077717
- Pathways
- Brown Fat Cell Differentiation
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